SCIENCE

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Science

What is Dihydromyricetin (DHM)

Dihydromyricetin (DHM) is a breakthrough natural ingredient from the Japanese raisin tree that supports liver health and helps combat alcohol's effects on the body. Research shows DHM enhances the liver's ability to process alcohol faster, reducing toxins that cause hangovers, while also protecting against inflammation linked to liver damage [1-3]. It’s your secret weapon for bouncing back faster and promoting long-term liver wellness [1].

For more information on the scientific benefits of DHM, please visit:

https://today.usc.edu/hangover-remedy-dhm-liver-protection-usc-study/

DHM + Piperine + Milk Thistle

This innovative formula combines dihydromyricetin (DHM), piperine, and milk thistle to protect and rejuvenate your liver while reducing alcohol's effects on your body. With this unique formulation, DHM speeds up alcohol breakdown and fights inflammation, piperine boosts nutrient absorption for maximum potency, and milk thistle shields the liver from toxins [1-5]. Together, these scientifically-backed ingredients work to detoxify, protect, and help you bounce back faster after a night out.

Flower

References:

1. https://today.usc.edu/hangover-remedy-dhm-liver-protection-usc-study/

2. Silva, J., Yu, X., Moradian, R., Folk, C., Spatz, M.H., Kim, P., Bhatti, A.A., Davies, D.L. and Liang, J., 2020. Dihydromyricetin protects the liver via changes in lipid metabolism and enhanced ethanol metabolism. Alcoholism: Clinical and Experimental Research, 44(5), pp.1046-1060.

3. Janilkarn-Urena, I., Idrissova, A., Zhang, M., VanDreal, M., Sanghavi, N., Skinner, S.G., Cheng, S., Zhang, Z., Watanabe, J., Asatryan, L. and Cadenas, E., 2023. Dihydromyricetin supplementation improves ethanol-induced lipid accumulation and inflammation. Frontiers in Nutrition, 10, p.1201007. 4. Wdowiak, K., Miklaszewski, A., Pietrzak, R. and Cielecka-Piontek, J., 2023. Amorphous System of Hesperetin and Piperine—Improvement of Apparent Solubility, Permeability, and Biological Activities. International Journal of Molecular Sciences, 24(5), p.4859.

Alcohol Metabolism and Liver Damage

Alcohol consumption causes hangovers and liver damage by overloading your liver with toxins like acetaldehyde, a byproduct of alcohol metabolism. These toxins lead to dehydration, inflammation, and oxidative stress, which cause hangover symptoms such as fatigue, nausea, and headaches [1,2]. Over time, heavy and/or frequent drinking can damage the liver, leading to fatty liver, inflammation, or scarring (cirrhosis), impairing your body’s natural detox process [3].

References:

1. https://sncs-prod-external.mayo.edu/hometown-health/speaking-of-health/effects-of-alcohol-on-your-health-and-liver

2. https://today.usc.edu/hangover-remedy-dhm-liver-protection-usc-study

3. Meza, V., Arnold, J., Díaz, L.A., Ayala Valverde, M., Idalsoaga, F., Ayares, G., Devuni, D. and Arab, J.P., 2022. Alcohol consumption: medical implications, the liver and beyond. Alcohol and Alcoholism, 57(3), pp.283-291.

Joshua Silva

Chief Science Advisor: Joshua Silva, PhD

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.